Abstract
ABSTRACTBackgroundInherited epidermolysis bullosa (EB) is a genetic disorder characterized by skin fragility and unique oral features.AimsTo provide (a) a complete review of the oral manifestations in those living with each type of inherited EB, (b) the current best practices for managing oral health care of people living with EB, (c) the current best practices on dental implant‐based oral rehabilitation for patients with recessive dystrophic EB (RDEB), and (d) the current best practice for managing local anesthesia, principles of sedation, and general anesthesia for children and adults with EB undergoing dental treatment.MethodsSystematic literature search, panel discussion including clinical experts and patient representatives from different centers around the world, external review, and guideline piloting.ResultsThis article has been divided into five chapters: (i) general information on EB for the oral health care professional, (ii) systematic literature review on the oral manifestations of EB, (iii) oral health care and dental treatment for children and adults living with EB—clinical practice guidelines, (iv) dental implants in patients with RDEB—clinical practice guidelines, and (v) sedation and anesthesia for adults and children with EB undergoing dental treatment—clinical practice guidelines.Each chapter provides recommendations on the management of the different clinical procedures within dental practice, highlighting the importance of patient‐clinician partnership, impact on quality of life, and the importance of follow‐up appointments. Guidance on the use on nonadhesive wound care products and emollients to reduce friction during patient care is provided.ConclusionsOral soft and hard tissue manifestations of inherited EB have unique patterns of involvement associated with each subtype of the condition. Understanding each subtype individually will help the professionals plan long‐term treatment approaches.
Highlights
Inherited epidermolysis bullosa (EB) is a genetic disorder characterized by skin fragility
This article has been divided into five chapters: (i) general information on EB for the oral health care professional, (ii) systematic literature review on the oral manifestations of EB, (iii) oral health care and dental treatment for children and adults living with EB—clinical practice guidelines, (iv) dental implants in patients with recessive dystrophic EB (RDEB)—clinical practice guidelines, and (v) sedation and anesthesia for adults and children with EB undergoing dental treatment—clinical practice guidelines
As part of their vision for working to ensure access to the best quality support and medical care for people living with EB, DEBRA International entrusts the development of clinical practice guideline (CPG) to health care professionals with significant experience in EB around the world
Summary
Inherited epidermolysis bullosa (EB) is a genetic disorder characterized by skin fragility. The International Dystrophic Epidermolysis Bullosa Research Association (DEBRA International) is the worldwide network of national groups working on behalf of those affected by EB As part of their vision for working to ensure access to the best quality support and medical care for people living with EB, DEBRA International entrusts the development of clinical practice guideline (CPG) to health care professionals with significant experience in EB around the world. Results: This article has been divided into five chapters: (i) general information on EB for the oral health care professional, (ii) systematic literature review on the oral manifestations of EB, (iii) oral health care and dental treatment for children and adults living with EB—clinical practice guidelines, (iv) dental implants in patients with RDEB—clinical practice guidelines, and (v) sedation and anesthesia for adults and children with EB undergoing dental treatment—clinical practice guidelines. Understanding each subtype individually will help the professionals plan longterm treatment approaches
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
