Abstract

Objective To investigate the influence of Qiliqiangxin capsule on the exercise tolerance in patients with chronic heart failure. Methods 86 patients with chronic heart failure were selected and recruited into a control group and an observation group randomly. The patients in the control group were given angiotensin-converting enzyme inhibitor, diuretic,carvedilol or metoprolol and dixina. The patients in the observation group were given Qiliqiangxin capsule on the basis of the control group. The change of exercise tolerance and left ventricular ejection fraction in all patients were detected after 4 weeks.Results The distance of walking in 6 minutes increased for all patients after 4 weeks' treatment(P<0.05), while the observation group increased more significantly than the control group(P<0.05). The left ventricular ejection fraction increased for all patients after therapy 4 weeks (P<0.05), while the observation group increased more obviously than the control group (P<0.05). The total excellent rate and effective rate in the observation group were both higher than the control group (P<0.05). Conclusion Qiliqiangxin capsule can increase the clinic curative effect by increasing the exercise tolerance and improving the heart function of patients with chronic heart failure. Key words: Qiliqiangxin capsule; Heart failure; Walking experiment in 6 minutes

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