Abstract
Background: Though painless abortion is a safe, effective and excellent method of artificial abortion, intravenous anesthesia cannot effectively expand the cervix. Hard and tight cervix often affects the operation and easily inducesabortion complications. Misoprostol can induce uterine contraction and soften the cervix. Objective: To investigate the clinical effect of misoprostol on abortion before and after painless induced abortion. Methods: 600 case pregnant women were divided into three groups: A, B and C, 200 case in each group. All patients were anesthetized. In group A, misoprostol 0.2 ug was placed in the posterior fornix of vagina 2 hours before the operation of induced abortion; in group B, misoprostol 0.2 ug was not only placed in the posterior fornix of vagina 2 hours before the operation of induced abortion but also taken orally 2 hours and 6 hours after the operation; in group C, misoprostol was not used before and after the operation. The operation time, intraoperative bleeding volume, postoperative bleeding, the percentage of cervical relaxation and the rate of incomplete abortion among the three groups were compared. Results: Compared with group A and group B, the operation time of group C was longer and the amount of bleeding was more (P 0.05). The duration of bleeding in group B was less than that in group A (P Conclusion: The use of misoprostol before and after painless induced abortion can not only shorten the time of operation, reduce intraoperative and postoperative vaginal bleeding, but also has not incurred incomplete abortion(primary outcome).
Highlights
Abortion as a remedy for contraceptive failure has been widely used
The purpose of this study is to explore the effect of misoprostol used before and after the painless abortion operation on the complications of painless induced abortion, and to find a safe and effective painless abortion
Comparison of the incidence of incomplete abortion in three groups, the difference was statistically significant (P < 0.05), respectively, group A (11/200, 5%), group, B (0/198, 0%) and group C (20/197, 10.2%), and above all group B had no residual tissues in uterine cavity, see Table 3
Summary
Abortion as a remedy for contraceptive failure has been widely used. With the improvement of anesthesia level, more and more early pregnant women choose painless abortion. Hard and tight cervix (especially in the first pregnant women) often affects the operation and causes complications, such as induced abortion syndrome, cervical injury, uterine perforation, bleeding, even incomplete abortion, long-term cervical dysfunction and so on, and intravenous anesthesia cannot effectively expand the cervix. Though painless abortion is a safe, effective and excellent method of artificial abortion, intravenous anesthesia cannot effectively expand the cervix. The operation time, intraoperative bleeding volume, postoperative bleeding, the percentage of cervical relaxation and the rate of incomplete abortion among the three groups were compared. Conclusion: The use of misoprostol before and after painless induced abortion can shorten the time of operation, reduce intraoperative and postoperative vaginal bleeding, and has not incurred incomplete abortion(primary outcome)
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