Clinical observatiom of corneal limbal stem cell auto-grafting,the transplantation of anmion and the pure removal of pterygium to treat the recurrent pterygium

Abstract

Objective The effect analyses by comparing and observing corneal limbal stem cell auto-grafting,the transplantation of flesh amnlon and the pure removal of pterygium to treat the recurrent pterygium.Method 166 cases of recurrent Pterygium( 176 eyes)is divides into 3 groups(named A,B,and C) randomly.Group A (with 67 cases, 72 eyes)is operated by removing the recurrent pterygium and corneal limbal stem cell auto-grafting.Group B (with 58 cases,59 eyes)is operated by removing the recurrent pterygium and the transplantation of flesh amnion.Group C (with 43 eases,45 eyes)is only operated by removing the pterygium.After operation,visits lasting 6-60 months are followed and comparations about the patients' symptoms,the wound matches and the pterygium relapses among the 3 groups are carried out.Result In group A,28 eyes relapsed from the whole 72 eyes,and the rate of relapsing is 39%.In group B,28 eyes relapsed from the whole 59 eyes,and the rate of relapsing is 47.5%.In group C,39 eyes relapsed from the whole 45 eyes,with the rate of relapsing 86.6%.Conclusion Compared with the effect of the pure removal pterygium to treat recurrent pterygium, there exist lower rates of relapsing in corneal limbai stem cell autografting and the transplantation of fresh amnion.Corneal limbal stem cell auto-grafting is more effective than the transplantation of flesh amnion in lowering the rate of relapsing recurrent pterygium.In addition, corneal iimbal stem cells are easily to be found and economical,and it is the effective option in treating recurrent pterygium. Key words: Pterygium ; Micro-surgical operation ; Corneal limbal stem cell autografting ; Amnion ;