Abstract

A premixed and lyophilized preparation of the more attenuated (Moraten) line of Enders' live measles virus vaccine combined with calf lymph smallpox vaccine was evaluated in a smallscale study in which the vaccine was given by jet gun. There was no evidence for interference between the two viruses. All the children responded serologically to both viruses and showed immune or vaccinoid reactions on challenge with smallpox vaccine given by the ordinary multiple puncture method. There was no apparent increase in clinical reaction beyond that expected following smallpox vaccine given alone.

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