Abstract
Purpose: The present study was performed to evaluate clinically, radiographically and histologically the effect of autologous platelet rich fibrin (PRF) and 1% alendronate (ALN) gel in alveolar ridge preservation after tooth extraction. Materials and method: In this study, thirty patients with teeth indicated for extraction were divided randomly into three groups: Group A: the patients received 1% ALN gel mixed with PRF as a grafting material for the extraction socket. Group B: the patients received PRF only and in Group C the socket left without any a grafting material. All patients were evaluated clinically and radiographically at; base line and after 3 months. Also, histological evaluation using bone core biopsy harvested at the re-entry surgery before implant placement. Results of the present study were recorded, tabulated and statistically analyzed. Results: Histological, clinical and radiographic findings showed a statistically significant difference in group A when compared to both group B and group C. Conclusions: The addition of ALN to PRF leaded to a noticeable socket preservation and reduction in the amount of bone resorption during the observation period of the study.
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