Abstract
The incidence of diabetes mellitus is increasing rapidly because of changes in dietetic habits and life style. Continuous research is being done by scientists of various fields in order to achieve an effective cure of the disease. A great deal of work has also been done by Ayurvedic research scholars on various herbal and mineral drugs to find an effective treatment for Prameha. Shilajatu is one such drug which has been described for the management of Prameha in Ayurveda texts. The present study was conducted to clinically assess the efficacy of Shilajatu in the management of Prameha. Twenty two diabetic patients were selected for the study. The results were assessed in terms of symptomatic relief on the basis of scoring system, laboratory investigations including fasting blood glucose, post prandial blood glucose, glycosylated Hb, urine sugar, and a Questionnaire on Quality of Life. Statistically highly significant improvement (p <0.001) was observed on FBS and PPBS. Â Statistically significant improvement was observed on urine sugar and glycosylated haemoglobin with p <0.05 and p<0.01 respectively. In terms of subjective parameters also, highly significant improvement, with p <0.001 was observed in Shaithilya, Mukha Sosha, Sandhi Shoola, Prabhuta Mutrata, Pipasa and Kshudha. Highly significant improvement was observed in quality of life statistically with p <0.001. The study revealed that Shilajatu can be used as a drug in the management of Prameha.
Highlights
Of the wide spectrum of disorders affecting people globally, Diabetes is growing in full pace and alarming the world as a non-infectious pandemic
The laboratory profile of the patients revealed that the trial drug namely, shilajatu was effective in lowering the mean fasting blood glucose levels with p
Similar effect was observed in mean urine sugar level with p
Summary
Of the wide spectrum of disorders affecting people globally, Diabetes is growing in full pace and alarming the world as a non-infectious pandemic. While the infectious disease burden decreases and development drives rapid changes in lifestyles, it is the developing regions that will see the greatest changes in the burden of diabetes.(2). Ayurveda is a rich treasure of safe materia medica which provides a promising field of drug research, especially in view of its vast treasury of drugs. Shilajatu is one such drug the use of which has been widely advocated for madumeha (~Diabetes mellitus) in ancient texts.(3) Shilajatu can be used either alone or in combination with other herbo mineral formulations, after its proper purification process.(4) The complete evidence based data on the efficacy of Shilajatu as madhumehahar has certain lacunae. An attempt has been made to study the effect of Shilajatu in madhumeha, which has been reported to possess hypoglycaemic property.(5) the present study was planned to generate evidence based data regarding efficacy of shilajatu in diabetes mellitus
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