Clinical effect of laparoscopic radical cystectomy with orthotopic neobladder

Abstract

Objective To investigate the clinical therapeutic effect of sigmoid neobladder after laparoscopic radical cystectomy in the treatment of invasive bladder cancer. Methods 21 patients with invasive bladder cancer accepted sigmoid neobladder after laparoscopic radical cystectomy and pelvic lymphadenectomy.The postoperative complications and clinical therapeutic effect were analyzed. Results All surgeries were completed successfully.The operation time was (245±125)min, blood lost was (98±45)mL.All the 21 patients were followed up for 3-24 months, mean of 12 months.Both side mild hydronephrosis in 6 cases (28.6%) and unilateral hydronephrosis in 1 case(0.5%). Average bladder reservoir was (548.8±221.6)mL, the maximum bladder pressure during the new bladder urine storage period was (2.26±0.24)kPa, the maximum bladder pressure during voiding period was (6.18±0.29)kPa, volume of residual urine was (87±52)mL.The mean maximum uroflow rate was (83.2±5.6)mL/s.The continence of micturition was 90.4% in day-time and 76.1% in night-time.1 case had urethral stricture and got better after the urethral dilatation. Conclusion The sigmoid neobladder after laparoscopic radical cystectomy has more reliable results, without serious postoperative complications and patients with high quality of life after operation.This operation may be applied in clinical practice. Key words: Laparoscopy; Bladder neoplasms; Radical cyatectomy; Sigmoid orthotopic neobladder