Abstract
AbstractNeovascular glaucoma (NVG) is a particularly aggressive type of secondary glaucoma that results from abnormal blood vessels and fibrovascular membranes that develop over the iris and iridocorneal angle. These changes can occur in the setting of underlying conditions associated with retinal ischemia, including proliferative diabetic retinopathy, central retinal vein occlusion, and ocular ischemic syndrome, among others. The neovessels, fibrovascular membrane, and subsequent peripheral anterior synechiae can obstruct aqueous humor outflow though the conventional outflow pathway and thereby cause elevations in intraocular pressure. NVG is typically associated with poorer visual prognosis compared to other types of glaucoma. A comprehensive history and physical examination are crucial for diagnosis, with special attention to assessing for neovascularization of the iris, neovascularization of the angle, and peripheral anterior synechiae. Ancillary testing including visual fields and optical coherence tomography can help in the diagnosis and ongoing monitoring of this potentially blinding condition. In this chapter, we review the essential components of the clinical evaluation for diagnosing and treating NVG in the outpatient office setting.KeywordsNeovascular glaucomaNeovascularization of the angleNeovascularization of the irisRubeosis iridisPeripheral anterior synechiae
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