Abstract

The COVID-19 pandemic holds widespread implications for global public health, economies, societies, and the practice of orthopedic surgery. As our knowledge of the transmissibility of SARS-CoV-2 and the symptomatology and management of COVID-19 expands, orthopedic surgeons must remain up to date on the latest medical evidence and surgical perspectives. While COVID-19 primarily manifests with pulmonary symptoms, cardiovascular, neurologic, and other major organ systems may also be affected and present with hallmark imaging findings. This article reviews initial and emerging literature on clinical characteristics and imaging findings of COVID-19.

Highlights

  • Since December 2019, infections with severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), a novel betacoronavirus strain responsible for coronavirus disease 2019 (COVID-19), rapidly progressed from an isolated cluster of cases in the Hubei province of east central China to a pandemic, with significant global health and economic repercussions [4, 5, 10, 24, 25, 27, 28, 44, 58, 80, 91]

  • As restrictions are eased nationally [1], it is critical that orthopedic surgeons remain aware of the clinical and radiographic findings associated with COVID-19 to best evaluate surgical patients

  • We summarize the most recent literature describing the clinical and imaging findings in order to assist orthopedic surgeons in navigating a clinical and practice management landscape permanently transformed by the pandemic

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Summary

Introduction

Since December 2019, infections with severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), a novel betacoronavirus strain responsible for coronavirus disease 2019 (COVID-19), rapidly progressed from an isolated cluster of cases in the Hubei province of east central China to a pandemic, with significant global health and economic repercussions [4, 5, 10, 24, 25, 27, 28, 44, 58, 80, 91]. By mid-June 2020, the World Health Organization (WHO) had declared over 4.3 million people infected worldwide, with nearly 300,000 deaths. In the USA, despite unprecedented social distancing and public health measures, over 1.3 million people were infected, with more than 100,000 deaths [21]. Public safety restrictions on semi-elective and elective office visits and surgical procedures during the COVID-19 pandemic have created a tremendous backlog (estimated at more than 1 million cases in 2 years) for orthopedic practices and have taken many practices to a tenuous economic precipice [4, 39]. As restrictions are eased nationally [1], it is critical that orthopedic surgeons remain aware of the clinical and radiographic findings associated with COVID-19 to best evaluate surgical patients. We summarize the most recent literature describing the clinical and imaging findings in order to assist orthopedic surgeons in navigating a clinical and practice management landscape permanently transformed by the pandemic

Cardiovascular manifestations Musculoskeletal and neurologic manifestations
Gastrointestinal manifestations
Pulmonary Manifestations
Cardiovascular Manifestations
Thromboembolic Complications
Neurologic Manifestations
Musculoskeletal Manifestations
Cytokine Storm
Gastrointestinal and Hepatic Manifestations
Findings
Renal Dysfunction
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