Abstract
Mastocytosis is a relatively rare group of diseases caused by the proliferation of mast cells in various organs and tissues. The article presents data on the etiology, pathogenesis, clinical presentations, diagnosis and differential diagnosis of mastocytosis, and own clinical observations. Presented clinical cases picture the features of the clinical course of the disease in different age groups. The first clinical case clearly shows the onset of the disease in early childhood (6 months), and misdiagnosis of this disease. The clinical picture of mastocytosis was wrongly assessed as a manifestation of atopic dermatitis, for which the patient received topical treatment without clinical effect. The second clinical observation is in 30 year old patient. The nature and spreading of the disease were assessed, proper treatment was administered. Both patients improved after treatment. Presented clinical observations reflect the importance of the problem in medical practice. Early diagnosis improves the prognosis of the disease and improves the quality of life.
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