Abstract
The diversity and low specifi city of clinical manifestations of COVID-19, as well as its widespread prevalence, present diffi culties for diff erential diagnosis, including conditions caused by drug overdose. The challenging experience of providing medical care during the coronavirus pandemic draws attention to the importance and necessity of further improving its diagnosis, especially in comorbid conditions. A clinical case of diff erential diagnosis of non- iatrogenic overdose of methotrexate in a patient with a preliminary diagnosis (virus unknown) is described: U07.2 (ICD-10) COVID-19.
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