Abstract

To analyze the clinical and epidemiological features of tuberculosis in children and adolescents in an infectious diseases reference hospital. A documental and retrospective study was carried out with 88 medical files in an infectious diseases reference hospital in the state of Ceará. Data were analyzed by univariate, bivariate and multivariate approaches. It was found that, depending on the tuberculosis type, its manifestations may vary. The logistic regression model considered only pulmonary tuberculosis due to a number of observations and included female sex (95% CI: 1.4-16.3), weight loss (95% CI: 1.8-26.3), bacilloscopic screening (95% CI: 1.5-16.6) and sputum collected (95% CI: 1.4-19.4) as possible predictors. Children and adolescents present different manifestations of the disease depending on the tuberculosis type that affects them. Knowing the most common features of each condition could enhance early diagnosis and, consequently, result in adequate treatment and care.

Highlights

  • Tuberculosis (TB) is a known tropical infectious disease and currently is the number one cause of death among the infectious conditions

  • El modelo de regresión logística consideró solo la tuberculosis pulmonar, debido a varias, observaciones e incluyó el género femenino (IC 95%: 1,4-16,3), la pérdida de peso (IC 95%: 1,8-26,3), la revisión baciloscopia y el esputo recolectado como posibles predictores

  • Confidentiality was guaranteed to each person whose medical file was used, and only data that were relevant to this study was gathered as established in the 466/12 resolution of the Brazilian National Health Council

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Summary

Introduction

Tuberculosis (TB) is a known tropical infectious disease and currently is the number one cause of death among the infectious conditions. In 2016, there was estimated 10.4 million new cases of TB all over the globe, and 6.9% of these cases were represented by people under 15 years old[1]. During the same year in Brazil, an incidence rate of 32.4 new cases of TB per 100 thousand habitants was identified. Following WHO initiative, many countries started publication on the childhood results from their TB programs; information on the subject is still scarce and several questions have not yet been addressed. Challenges such as early and/or proper diagnosis, early treatment and adequate notification difficult the publication of accurate data[3]

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