Abstract

Psoriatic arthritis (PsA) is an inflammatory arthritis with multiple manifestations: peripheral/axial arthritis, enthesitis, dactylitis, psoriasis, and nail involvement. From having an agreed upon classification criteria in 2006, the assessment of PsA has advanced from uncertainties to development and validation of numerous specific outcome measures. The Group for Research and Assessment of Psoriasis and Psoriatic arthritis (GRAPPA) has spearheaded the development of a core domain set and is now working on a core outcome measurement set to standardize outcome measures for PsA, that will provide guidance for use of instruments in randomized controlled trials (RCTs) and longitudinal observational studies (LOS). This article summarizes and updates these work processes to improve assessment of this multisystem complex rheumatologic disease.

Highlights

  • Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis

  • Subsequent cohorts from different centers identified different proportions of PsA patients divided into asymmetrical oligoarthritis and symmetrical polyarthritis subgroups [13, 14], possibly because of inclusion of differing proportions of rheumatoid factor (RF) negative rheumatoid arthritis (RA) patients based on the Moll and Wright case definition [13]

  • Physician performed by inspection of the patient’s nails Nail Psoriasis Severity Index (NAPSI) (0–80 finger nails only; or 0–160 finger and toe nails) Modified Nail Psoriasis Severity Index (0–130) Target NAPSI score (0–13) VAS Nail Psoriasis

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Summary

Classification and Outcome Measures for Psoriatic Arthritis

Ying Ying Leung 1*, Alexis Ogdie 2, Ana-Maria Orbai 3, William Tillett 4, Laura C. Coates 5, Vibeke Strand 6, Philip Mease 7 and Dafna D. Reviewed by: Alexandre Sepriano, Leiden University Medical Center, Netherlands Anabela Barcelos, Centro Hospitalar Baixo Vouga,. Specialty section: This article was submitted to Rheumatology, a section of the journal

Frontiers in Medicine
INTRODUCTION
Classification Criteria
Classification and Outcome Measures for PsA
Pros and Cons
Psoriasis or personal history of psoriasis
Measurement of Meaningful Outcomes in PsA
SKIN DISEASE ACTIVITY
PATIENT GLOBAL
PHYSICAL FUNCTION
SYSTEMIC INFLAMMATION
Development of Core Domain Set for PsA
Development of Core Outcome Measurement Set for PsA
Findings
CONCLUSION
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