Abstract
The baroreflex regulation of arterial blood pressure and heart rate was examined in dogs with acrylamide-induced peripheral neuropathy. In anaesthetized animals the carotid sinuses were isolated from the systemic circulation and perfused. The carotid sinus and vagus nerves were kept intact. The maximum baroreflex gain (the ratio of the change in systemic pressure to a change in sinus pressure) was significantly greater in the treated animals. A step increase in carotid sinus pressure produced long periods of asystole and sustained bradycardia in the animals with neuropathy. The alterations in the baroreceptor reflex responses were consistent with dysfunction of baroreceptor fibres in the vagus.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
