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Article1 June 1950CHRONIC PULMONARY GRANULOMATOSIS IN RESIDENTS OF A COMMUNITY NEAR A BERYLLIUM PLANT: THREE AUTOPSIED CASESCHARLES CHESNER, M.D.CHARLES CHESNER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-32-6-1028 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptINTRODUCTIONThe purpose of this paper is to alert the physicians to a chronic type of pulmonary disease of high fatality occurring in individuals living in a community where beryllium is produced.In 1943 and again in 1945, Van Ordstrand1, 2and associates described cases of acute beryllium poisoning in workers in plants producing beryllium, its compounds and alloys. One of the papers2recorded the autopsy findings in five fatal cases. The signs and symptoms of the acute beryllium intoxication began while the patients were actively engaged in working with beryllium and, in the non-fatal cases, cleared up when the...Bibliography1. Van OrdstrandHughesCarmody HSRMG: Chemical pneumonia in workers extracting beryllium oxide, report of three cases, Clev. Clin. Quart. 10: 10, 1943. CrossrefGoogle Scholar2. Van OrdstrandHughesDeNardiCarmody HSRJMMG: Beryllium poisoning, J. A. M. A. 129: 1084, 1945. CrossrefMedlineGoogle Scholar3. HardyTabershaw HLIR: Delayed chemical pneumonitis occurring in workers exposed to beryllium compounds, J. Ind. Hyg. and Tox. 28: 197, 1946. MedlineGoogle Scholar4. Hardy HL: New clinical syndrome: delayed chemical pneumonitis occurring in workers exposed to beryllium compounds, Bull. N. E. M. Center 9: 16, 1947. MedlineGoogle Scholar5. Hardy HL: Pulmonary disease in industry, Trans. 43rd Ann. Meet. Nat. Tuberc. Assoc., 1947. Google Scholar6. Gardner LU: Generalized pulmonary granulomatosis occurring among workers believed to be exposed to beryllium or its compounds, Trans. 11th Annual Meet. Ind. Hyg. Found. Am., 1946. Google Scholar7. MartlandBrodkinMartland HSHAHS: Occupational beryllium poisoning in N. J., J. Med. N. J., 45: 5, 1948. Google Scholar8. Higgins HL: Pulmonary sarcoidosis, Conn. M. J. 11: 330, 1947. MedlineGoogle Scholar9. DeNardiVan OrdstrandCarmody JMHSM: Chronic pulmonary granulomatosis, Am. J. Med. 7: 345-355, 1949. CrossrefMedlineGoogle Scholar10. HyslopPalmesAlfredMonacoFairhall FEDWCRALT: Toxicology of beryllium, Nat. Inst. Health Bull. No. 181, U. S. Pub. Health Service, 1943. Google Scholar11. DeNardi JM: Personal communication. Google Scholar12. Pascucci LM: Pulmonary disease in workers exposed to beryllium compounds: its roentgen characteristics, Radiology 50: 23, 1948. CrossrefMedlineGoogle Scholar13. CholakHubbard JDM: Spectographic determination of beryllium in biological material and in air, Analyt. Chem. 20: 73, 1948. CrossrefGoogle Scholar14. Dutra FR, Kettering Laboratory, Cincinnati, Ohio: Personal communication. Google Scholar15. Durkan TM, Asst. Director of the Saranac Laboratory, New York State: Personal communication. Google Scholar16. Vorwald AJ, Director, Saranac Laboratory, New York State: Analysis of tissue and comments. Google Scholar17. Dutra FR: The pneumonitis and granulomatosis peculiar to beryllium workers, Am. J. Path. 24: 1137-1150, 1948. MedlineGoogle Scholar18. DutraCholakHubbard FRJFDM: Value of beryllium determinations in the diagnosis of berylliosis, Am. J. Clin. Path. 19: 229-234, 1949. CrossrefMedlineGoogle Scholar19. HamiltonHardy AHL: Industrial toxicology, 2nd Ed., 1949, Paul B. Hoeber, chapter 10. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Lorain, Ohio*Received for publication January 11, 1949.From St. Joseph Hospital, Lorain, Ohio. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byInnate and Adaptive Immunity in Noninfectious Granulomatous Lung DiseaseChronic Beryllium DiseaseExposure Factors Associated With Chronic Beryllium Disease Development in Beryllium BioBank ParticipantsBeryllium DiseaseUnited Kingdom Beryllium Registry: mortality and autopsy study.Take-Home Toxin PathwayPathology of pulmonary sarcoidosisTransmission of occupational disease to family contactsAssessment of a Scheme for Prioritizing Inorganic Toxicants by Using Signs-and-Symptoms AnalysisImmunological aspects of exposure to emissions from burning coal of high beryllium contentPulmonary and hepatic granulomatous disorders due to the inhalation of cement and mica dusts.Beryllium in the EnvironmentAuf anorganische Stäube mit geringen oder fehlendem Quarzgehalt zurückgehende LungenveränderungenWidening perspectives of occupational lung diseaseCRITICAL EVALUATION OF DISEASE HAZARDS ASSOCIATED WITH COMMUNITY ASBESTOS AIR POLLUTIONBeryllium diseaseChronic beryllium diseaseEnvironmental epidemiology. 3. Community effects of nonoccupational environmental asbestos exposure.Status of Air Pollution Health Research, 1966Beryllium PoisoningZur normalen und pathologischen Histologie hautnaher LymphknotenBERYLLIUM DISEASE - EXPERIENCE WITH INVESTIGATION REQUIRED TO ESTABLISH ETIOLOGY OF OCCUPATIONAL DISEASECor pulmonaleCor pulmonaleBeryllium diseaseDie PneumonienPULMONARY DISEASE IN RELATION TO METALLIC OXIDESBerylliumBERYLLIUM GRANULOMATOSIS COMPLICATED BY TUBERCULOSIS: REPORT OF A CASE TREATED WITH ACTH*R. LOWRY DOBSON, JOHN C. WEAVER, LEON LEWIS, F.A.C.P.Occupational Medicine 1 June 1950Volume 32, Issue 6Page: 1028-1048KeywordsAutopsyIntoxicationPulmonary diseasesResearch laboratoriesSigns and symptoms ePublished: 1 December 2008 Issue Published: 1 June 1950 PDF downloadLoading ...

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