Abstract
The occurrence of acute leukemia in patients with chronic lymphocytic leukemia is being reported with increasing frequency.<sup>1-31</sup>Although the majority of these cases have been described as "acute blastic terminal phase" or as straightforward lymphoblastic in nature, a substantial number of patients' terminal acute leukemia has been described as myeloblastic, monocytic, and myelomonocytic, which raises the question of a separate origin to this terminal acute leukemia. A review and analysis of the literature are the substance of this report. <h3>LITERATURE REVIEW</h3> In 1949, Lawrence et al<sup>1</sup>described 100 patients with chronic lymphocytic leukemia treated with radioactive phosphorus (<sup>32</sup>P). Fifty-eight of the patients also received local radiation to spleen or lymph nodes either prior to or subsequent to the<sup>32</sup>P therapy. Two of the 100 patients developed "acute leukemia with increased numbers of blast cells in the blood smear" (type not stated). The following year, another report
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
