Abstract
9 patients with chronic idiopathic jaundice are described. 7 had Dubin-Johnson's syndrome, and 2 Rotor's syndrome. 6 of those with Dubin-Johnson's syndrome were from the Madang District of New Guinea and were all diagnosed within one year. Mechanisms are proposed by which this high local incidence may have arisen, but further genetic studies would be needed to decide the most likely one. This high incidence is contrasted with the apparent absence of these syndromes in the Highlands people of Papua and New Guinea.
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