Abstract

Chronic granulomatous disease (CGD) is a primary immune deficiency that characterized with recurrent infections and granuloma formation. A variety of autoimmune disorders and immune-mediated phenomena such as inflammatory bowel disease, discoid lupus erythematous, juvenile idiopathic arthritis, Ig A nephropathy, sarcoidosis, rheumatoid arthritis, idiopathic thrombocytopenia, eosinophilic cystitis, celiac disease, autoimmune hemolytic anemia and antiphospholipid syndrome have been associated with CGD.

Highlights

  • Chronic granulomatous disease (CGD) is a primary immune deficiency that characterized with recurrent infections and granuloma formation

  • Chronic granulomatous disease associated with systemic lupus erythematosus and systemic onset juvenile idiopathic arthritis

  • A variety of autoimmune disorders and immune-mediated phenomena such as inflammatory bowel disease, discoid lupus erythematous, juvenile idiopathic arthritis, Ig A nephropathy, sarcoidosis, rheumatoid arthritis, idiopathic thrombocytopenia, eosinophilic cystitis, celiac disease, autoimmune hemolytic anemia and antiphospholipid syndrome have been associated with CGD

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Summary

Introduction

Chronic granulomatous disease (CGD) is a primary immune deficiency that characterized with recurrent infections and granuloma formation. A variety of autoimmune disorders and immune-mediated phenomena such as inflammatory bowel disease, discoid lupus erythematous, juvenile idiopathic arthritis, Ig A nephropathy, sarcoidosis, rheumatoid arthritis, idiopathic thrombocytopenia, eosinophilic cystitis, celiac disease, autoimmune hemolytic anemia and antiphospholipid syndrome have been associated with CGD

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