Abstract
This study aimed to assess the regularity of the choroidoscleral interface (CSI) using a novel parameter, CSI irregularity index, before and after epiretinal membrane (ERM) surgery. This study included 36 patients with idiopathic ERM who underwent pars plana vitrectomy and ERM removal. All subjects underwent ocular examinations at baseline and at 1, 2, 4, and 6 months after surgery. The regular contour of the CSI was found in 14 patients (38.9%); mean CSI irregularity index was 14.84 ± 11.01 in this group. The irregular contour of the CSI was found in 22 patients (61.1%); mean CSI irregularity index was 33.96 ± 20.64 in this group. The CSI irregularity index decreased gradually after ERM surgery, and was correlated with postoperative best-corrected visual acuity. The CSI irregularity index could serve as a surrogate marker to quantitatively represent the CSI morphology. We observed the gradual decrease of the CSI irregularity index after ERM surgery in quantitative manner. This study showed correlations between the CSI irregularity index and visual outcomes after ERM surgery. Our results suggest that the CSI irregularity index might be an intuitive anatomic indicator of the CSI and might be useful as a possible prognostic marker for patients undergoing ERM surgery.
Highlights
Epiretinal membrane (ERM) is one of the most common retinal diseases, characterized by fibrocellular tissue proliferation on the inner retinal surface[1,2,3]
Inner retinal irregularity index and inner retinal layer thickness were reportedly associated with poor visual outcomes; in contrast, retinal contraction was associated with good visual outcomes after epiretinal membrane (ERM) surgery[10,11,16]
The bowl-shaped contour of the choroidoscleral interface (CSI) was found in 14 patients (38.9%); the mean CSI irregularity index was 14.84 ± 11.01 in this group
Summary
Epiretinal membrane (ERM) is one of the most common retinal diseases, characterized by fibrocellular tissue proliferation on the inner retinal surface[1,2,3]. Previous studies have attempted to identify prognostic factors that indicate which patients exhibit a better outcome following ERM surgery[9,10,11,12,13,14,15,16]. Many studies have focused on the relationship between central foveal thickness and visual outcome after ERM surgery; the results have been inconsistent[12,13,14]. Inner retinal deformation has been suggested as an important prognostic factor in ERM. There is limited information regarding CSI before and after ERM surgery; notably, previous researchers have evaluated CSI solely in a qualitative manner.
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