Abstract
As early as 1887, Moeli<sup>1</sup>reported a case of bilateral Argyll Robertson pupils associated with a tumor of the third ventricle. Since then several similar cases have been described.<sup>2</sup>The older cases, which occurred before the introduction of the Wassermann test, are of course not quite convincing; but in recent years the Argyll Robertson sign has been found repeatedly in various abnormal conditions of the nervous system in which it has seemed possible to exclude syphilitic infection, and it is now evident that it is not a specific sign of syphilis, but may result from lesions of various types. These lesions have been found most frequently in the anterior part of the midbrain and the third ventricle. The Argyll Robertson pupil has been described in brain tumors,<sup>3</sup>multiple sclerosis,<sup>4</sup>epidemic encephalitis,<sup>5</sup>syringomyelia,<sup>6</sup>chronic alcoholism,<sup>7</sup>hypertrophic interstitial neuritis,<sup>8</sup>vascular lesions<sup>9</sup>and in
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