Abstract
Chlordane is a cyclodiene insecticide that was introduced in 1945. In recent years its use in the U.S.A. has been limited to termite control. The metabolism of chlordane and its residues in animals following oral intake has been documented. However, there are no published studies on chlordane residues in animals following inhalation exposure. This study sought to investigate the residues in the blood and tissues of rats and monkeys (both sexes) during 90-day subchronic inhalation exposure to technical chlordane. The effect of discontinued exposure on the depuration of residues in rats was also investigated.
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