Abstract
The efficacy of the UV-H2O2 treatment to degrade the antibiotic chloramphenicol (CHL) was investigated at 20 °C using a low-pressure mercury lamp as UV source. A two-level factorial design was used to study the effects of initial CHL (c0 = 4080 mg L1) and H2O2 (h0 = 2050 mM) concentrations, reaction time (t = 3070 min) and irradiance level (I = 400800 μW cm2) on CHL degradation. Under the best conditions (c0 = 40 mg L1, h0 = 20 mM, t = 70 min, I = 800 μW cm2), almost 96% of the antibiotic was degraded. No residual antibiotic activity was detected in the treated solution, thereby confirming the efficacy of the UV-H2O2 process.
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