Abstract
The ability of a vector to ferry gene into targeted cells is the premise of improving gene-transfer efficiency. Chitosan, a naturally occurring cationic polysaccharide, has been shown to excel in transcellular transport. This attribute has been fully reflected in chitosan-mediated gene transfection systems. The objective of this review is to summarize the recent encouraging advances in unveiling the mechanism of cell entry and application of chitosan and its derivatives as novel non-viral vectors. It is our belief that researchers will uncover more truth about chitosan-based vector and realize the long-term goal of gene transfection--produce the desired clinical effect.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
