Abstract
Chiral metal complexes render new breakthroughs in chemical sciences by providing stereoselective, robust and enantiomerically pure compounds and their applications as pharmaceuticals, diagnostic agents, in supramolecular assemblies, enzyme catalysis, biomimetic model systems and as nucleic acid probes. Recent progress in interdisciplinary research has motivated researchers to look for innovative measures to improve the quality of life and spurred various efforts directed towards the creation of molecularly engineered novel synthetic agents. The use of food additives, flavors, agrochemicals, pharmaceuticals and new medical diagnostic agents is indispensible in modern era, therefore to foster this concept, synthetic methodologies have to be monitored carefully. The growth of this core technology has given rise to enormous economic potential in the manufacture of pharmaceuticals, fungicides, flavors, and fragrances. As this subject is an essential component of molecular science, this review deals with the most representative contributions in the field of chiral transition metal complexes, their synthetic methodology and biological applications.
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