Abstract
Chemosignaling is widespread among animals as tool for regulation of synecological interactions. Evolutional conservatism of such signaling allows us to suggest that same chemosignals play an important role in different animal species including human beings. Aversion/attraction of mouse pheromone 2,5- dimethylpyrazine (2,5-DMP) and 2,3-dimethylpyrazine (2,3-DMP) for CBA and C57BL/6 mice was studied in T-maze. It is shown that intact males and females of both strains under choice condition prefer 2,3-DMP to water and 2,5-DMP. They also prefer water to 2,5-DMP Stress after swimming modifies behavior in T-maze: all preferences disappear in C57BL/6 males and remain without changes in CBA males. Importance of behavioral changes obtained here under stress condition is discussed. Detailed studies of the preference modulation with recently shown other effects of 2,5-DMP could connect specific sensitivity to chemosignals with the pheromone, stress and genotype.
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