Abstract
Curcuma zedoaria (Berg.), belongs to the Zingiberaceae family, is one of the medicinal plants that is found in Southeast Asia. This plant is known as “Nghe tim” in Vietnam; and a decoction of its rhizomes has been used traditionally for the cure flatulence, fatigue, and hepatitis. Previously, some studies on the chemical constituent of the rhizomes of C. zedoaria have reported plenty of curcuminoids and sesquiterpenoids together with their derivatives, which have shown a lot of various bioactivities such as antiproliferative characteristic, anti-ulcer, antioxidant and antibacterial potential. By chromatography column method along with preparative thin layer chromatography on a normal phase silica gel on the EtOAc extract of the rhizomes of Curcuma zedoaria, we have isolated five pure compounds. Their chemical structures have been elucidated by NMR techniques and comparison with publishing data that have determined to be gajustulactone A (1), isozedoarondiol (2), neolitacumone (3), β-sitosterol (4), and β-stigmasterol (5). The results of this study have contributed to the scientific data system on the chemical composition of Vietnamese medicinal plants, especially the rhizomes of Curcuma zedoaria grown in Tinh Bien, An Giang. Therefore, there is more evidence to continue screening studies to detect interesting biological activities from this species.
Highlights
of the medicinal plants found in Southeast Asia
a decoction of its rhizomes has been traditionally used for the cure flatulence
this is the first time they were reported from rhizomes of Curcuma zedoaria
Summary
TÓM TẮT Loài cây Curcuma zedoaria, thuộc họ Gừng (Zingiberaceae), là một trong những loài dược liệu được tìm thấy chủ yếu ở các nước Đông Nam Á. Ở Việt Nam, loài cây này có tên là Nghệ tím và phần củ của loài này được sử dụng nhiều trong các bài thuốc dân gian để chữa các bệnh đầy hơi, mệt mỏi và viêm gan. Kết quả nghiên cứu này đã góp phần đóng góp vào hệ thống dữ liệu khoa học về thành phần hoá học các cây thuốc Việt Nam, đặc biệt là củ Nghệ tím được trồng ở vùng Tịnh Biên, An Giang. Đây là bài báo công bố mở được phát hành theo các điều khoản của the Creative Commons Attribution 4.0 International license
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