Abstract
Cytoplasmic lipid droplets (CLDs) are major metabolic hubs in most cell types. These dynamic organelles regulate multiple aspects of cellular lipid homeostasis, including lipid storage and utilization, protecting from lipotoxicity, and lipid signaling. CLDs in specific cell types serve distinct roles depending on the physiological function of the tissue in regulating cellular and systemic lipid and energy homeostasis. Therefore, an imbalance in the storage or utilization of lipid in CLDs in major metabolic tissues can contribute to diseases such as nonalcoholic fatty liver disease (NAFLD), Type II diabetes, and obesity. The regulation of intracellular lipid storage and utilization is thereby essential to prevent abnormal cellular and systemic lipid levels and its associated pathological consequences.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
