Abstract
Cannabis sativa derivatives (marijuana, hashish) are currently the most frequently self-administered “soft narcotics” worldwide. Δ9-Tetrahydrocannabinol (THC), as other psychoactive substances, leads to a chronic and recurrent central nervous system (CNS) disease, complex in terms of its etiology, molecular mechanisms, clinical course, and treatment. This phenomenon is thought to be influenced by several concurrently acting genetic, molecular, psychological, and social factors, but the molecular aspects of this process are not fully known yet.
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