Abstract
Allylic fluorides are key components of several bioactive molecules and are used in the biological, medicinal, and agrochemical fields. This chapter describes different synthetic strategies developed in the last decade (starting from 2008) for the introduction of a fluorine atom in the allylic position of an organic molecule. The information is organized by the synthetic approach and includes dehydroxyfluorination of allylic alcohols, fluorination of allylic halides, CH fluorination reactions, fluorodesilylation of allyl silanes, synthesis of allyl fluorides from allyl carbonates, formation of allylic CF bonds from allyl p-nitrobenzoates, fluorination of allylic trichloroacetimidates, organoselenium-catalyzed oxidative allylic fluorination with electrophilic NF reagent, allylic fluorination of cinnamyl phosphorothioate esters, cooperative allylic fluorination: combination of nucleophilic and electrophilic sources, and synthesis of allyl-fluorinated homoallylic alcohols.
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