Abstract

Pain both acute and chronic remains a significant health problem that affects not only the spinal cord injured (SCI) patient’s quality of life but also the care givers. Thus gaining a greater understanding of the mechanisms underlying the development pain following trauma is critical for the development of therapeutic interventions to help attenuate pain development and pain maintenance. To do this, animal models have been developed that demonstrate reproducible changes in threshold to mechanical and thermal stimuli. This chapter focuses on the different behavioral tests used to indicate an increase in sensitivity to formerly nonnoxious stimuli, i.e. “pain behaviors” in rodent models of SCI.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.