Abstract
Triazole is a well-known scaffold widely used in drug design and novel drug discovery. It is a five-membered unsaturated ring composed of three nitrogen atoms and two carbon atoms, which has remarkable stability under acid and alkali hydrolysis and redox conditions. 1,2,3-Triazole can be used as a bioisostere of various groups and has a variety of pharmacologic activities. This chapter focuses on applications of 1,2,3-triazole as a bioisostere. We also discuss the pharmacologic activities of 1,2,3-triazole. These may provide information for further research into 1,2,3-triazole in chemistry and biology, and help to develop more efficient and less toxic drugs to treat disease.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
