Abstract
Subjects with sensitive skin report exaggerated reactions when their skin is in contact with cosmetics, soaps, and sunscreens, and they often report worsening after exposure to a dry and cold climate. Epidemiological studies have been carried out to assess whether there is a correlation with sex, age, skin type, or race and are described elsewhere in this book. Subjects with sensitive skin may have a thinner stratum corneum with a reduced corneocyte area causing a higher transcutaneous penetration of water soluble chemicals.1 Frosch and Kligman,2 by testing different irritants, showed a 14% incidence of sensitive skin in the normal population, likely correlated to a thin permeable stratum corneum which make these subjects more susceptible to chemical irritation.
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