Abstract
The assessment of mode of inheritance is paramount for understanding the familial aggregation of a trait. Related individuals might express similar phenotypes because of a common genetic constitution or because of the transmission and sharing of cultural and environmental factors, or the similarity might be the result of interactions among these forces. The principal theoretical models of inheritance of quantitative traits are: (1) the trait expression is because of segregation at a single locus or a few major loci; (2) the variation in the trait values results from a blend of many approximately equal small genetic effects plus a myriad of environmental perturbations; (3) the trait expression reflects a combination of major gene and multifactorial components; and (4) the trait values behave as in sporadic models, which are special limiting cases where no transmission takes place between parents and offspring or among siblings and thus serve to portray purely random environmental effects.
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