Abstract
Apoptosis and necrosis are believed to be two significant pathways contributing to cell death. Molecular mechanisms of these pathways are studied extensively. However, recent research discovered various other forms of cell death via different pathways. Apoptotic cell death leads to eliminating dead cells without affecting or with minimal damage to the surrounding cells. Necrosis is characterized by unrestrained cell death, usually caused due to injury or inflammation that leads to the leakage of the contents to the surrounding cells or tissues and consequently damaging the healthy tissue. Necroptosis is a combination of necrosis and apoptotic pathways, which contribute to cell death. Many molecular level pathways overlap between apoptosis, necrosis, and necroptosis. This chapter aims to provide a basic understanding of the molecular level mechanisms involved in apoptosis, necrosis, and necroptosis. This chapter provides information about the significant forms of cell death pathways and allows the reader to compare the different pathways.
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