Abstract
How and when property data are used can have a great impact on a project. Successful property strategies include the following: start assessing properties early, profile properties of new compounds rapidly, develop structure-property relationships, optimize activity and properties in parallel, use single-property assays to guide specific modifications, improve bioassays and their interpretation, customize assays for specific research questions, diagnose the root cause of pharmacokinetics liabilities, and use human materials to predict human performance.
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