Abstract
Glucose transporters are proteins, which facilitate glucose (and related substance) transport across cell membrane. As glucose is vital to all cells of body, so are glucose transporters. Recent advances in technology have revealed lot of new information about structural and functional characteristics of these proteins. There are three families of glucose transporters, GLUTs, SGLTs, and newly added SWEETs. These families are further divided in several subtypes. Individual transporters differ in their gating characteristics, transport kinetics, and expression regulatory mechanisms. Some of these transporters have been implicated in pathophysiology of various diseases. Accordingly, they are potential targets of several drug therapies. Further, there is a pressing need of studies to reveal more about their function and distribution. This chapter gives an updated account of information, which may be useful to researchers involved in pharmacology and biochemistry.
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