Abstract

This chapter discusses the chemosensors for detecting molecules using modified CDs. There has been considerable interest in the development as an important application of supramolecular chemistry. The chapter reviews the molecule sensing abilities of a number of modified CDs, CD-peptide conjugates, and CD-protein conjugates. The conformational change of dansyl-leucine modified CD is provided, as it is a useful example to understand the sensing behavior of fluorophore modified CD. The molecule sensing properties of fluorescent cyclodextrins is discussed with mathematical equations and figures. The effect of protein environment on molecule sensing of chemosensors is given. The chapter shows that fluorescent CD is useful for detecting molecules via molecular recognition, which in turn helps in designing chemosensors that show a variety of responses to guests. The application of a series of fluorescent CD in a chemosensor for an array can be envisaged as one of the many practical uses of the molecule sensing abilities of the chemosensors.

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