Abstract
The incidence of skin cancer has grown over the decades for both non-melanoma and melanoma cancers. One out of every three diagnosed cases of cancer is non-melanoma skin cancer. Among skin cancers, melanoma remains a fatal disease. Surgical excision is often used to remove cancer, but topical therapy represents an appropriate treatment method, because it is not invasive, may reach a wide area of skin, and does not cause hypertrophic scars. The skin exerts a barrier function, mainly through the stratum corneum. Thus, topical application nanocarriers should overcome this and, through penetration pathways, reach the cancer and deliver anticancer drugs. Several types of carriers can improve drug/therapy limitations and may utilize local characteristics to increase efficacy. Also, photodynamic therapy works with photosensitizer delivered at the cancer site following irradiation, which destroys cancer cells. This chapter summarizes alternatives for effective and convenient treatments of skin cancer, encompassing nanocarriers with a focus on specificity and non-invasive approaches, enabling a cure.
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