Abstract
Background and Objective:This study was designed to identify the changing trends in Anti-psychotic prescription pattern in Pakistan. It was part of the research project Research on East Asian Psychotropic Prescription Pattern (REAP) carried out to identify the prescription patterns of schizophrenic patients in different countries located in Asia.Our objective was to assess the trend and change of psychotropic drug prescriptions for patients with schizophrenia.Methods:The design of the study was quantitative and of descriptive epidemiology. This study was carried out from 30th March 2017. Data was collected on a unified protocol by the Psychiatrists from Pakistan. Three (3) centers i.e., Lahore, Karachi and Islamabad provided the data. Indoor and outdoor cases with Schizophrenia were recruited. A web based recording system for collection of data done at Taipei Taiwan, and statistical analysis was performed and transferred to all participating centers including Pakistan.Results:The main findings of the study were that majority of the patients were prescribed antipsychotic poly pharmacy drug. It was also found that Anxiolytics, anti-depressants and Anti-parkinsonian drugs were also co-prescribed.Conclusion:It was concluded that antipsychotic poly pharmacy along with Anxiolytics, anti-depressants and Anti-parkinsonian drugs were prescribed to patients with schizophrenia in Pakistan.
Highlights
International Collaborative Studies on Psychotropic Prescription, a Research on East Asian Psychotropic Prescription Pattern (REAP) is the largest and the longest international collaborative research project in Asia
Another study on relation of antipsychotic polypharmacy and quality of life in patients with Schizophrenia in China suggested that the rate of Antipsychotic PolyPharmacy (APP) prescription was 31 with 89% on two antipsychotics and 10.4% received three or more antipsychotics
The findings suggested that the use of typical and typical antipsychotic drugs is 15.3% and 31.6% respectively, whereas the use of polypharmacy is 51.7%
Summary
International Collaborative Studies on Psychotropic Prescription, a Research on East Asian Psychotropic Prescription Pattern (REAP) is the largest and the longest international collaborative research project in Asia. The third survey was carried out in 2008 in China, Korea, Japan, Taiwan, Hong Kong, Singapore, Thailand, Malaysia and India This survey was conducted on the use of antipsychotic drugs. With the participation of India, Malaysia and Thailand, REAP became the research group covering almost all the countries of Asia This survey showed that SGA’s are the main antipsychotic drugs for the treatment of Schizophrenia in Asia.[3] Another survey on the use of antidepressants was conducted in 2014 by East Asia and South Asia.[4,5]. Korea and Singapore during this period.[7] Another REAP study was conducted on the prescribing pattern of antipsychotic medications in patients with Schizophrenia in a tertiary care hospital in India. The objective of current study was to assess the trend and change of psychotropic drug prescriptions for patients with schizophrenia
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