Abstract
The concentration of the level of cytokines in saliva depends on the form of stomatitis, which is confirmed by the presence of a relationship between the concentrations of TNFα and IL-1β, and this relationship is direct and varies depending on the form of stomatitis, which indicates a violation of immunoregulatory mechanisms in chronic recurrent forms of stomatitis.
Highlights
The concentration of the level of cytokines in saliva depends on the form of stomatitis, which is confirmed by the presence of a relationship between the concentrations of TNFα and IL-1β, and this relationship is direct and varies depending on the form of stomatitis, which indicates a violation of immunoregulatory mechanisms in chronic recurrent forms of stomatitis
The study of the cytokine status of the oral secretion is difficult to overestimate, since it reflects the individual primary response to a bacterial and viral agent, allows you to assess the nature of the process, predict the outcome of the disease in many bacterial and viral infections of the oral cavity, and allows you to objectively evaluate the effectiveness treatment [2,5].The clinical study of the level of cytokines in the oral cavity is devoted to isolated works related to the pathology of the oral mucosa [3, 4]
Group I - 52 children with acute stomatitis and Group II - 22 children with chronic recurrent stomatitis, 20 healthy children of comparable age made up the control group
Summary
The concentration of the level of cytokines in saliva depends on the form of stomatitis, which is confirmed by the presence of a relationship between the concentrations of TNFα and IL-1β, and this relationship is direct and varies depending on the form of stomatitis, which indicates a violation of immunoregulatory mechanisms in chronic recurrent forms of stomatitis. The study of the cytokine status of the oral secretion is difficult to overestimate, since it reflects the individual primary response to a bacterial and viral agent, allows you to assess the nature of the process, predict the outcome of the disease in many bacterial and viral infections of the oral cavity, and allows you to objectively evaluate the effectiveness treatment [2,5].The clinical study of the level of cytokines in the oral cavity is devoted to isolated works related to the pathology of the oral mucosa [3, 4] In this regard, the goal of our study was: To study the spectrum of cytokines of the oral cavity secretion in children and their prognostic value in the pathogenesis of acute and chronic recurrent stomatitis
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