Abstract
Objective: Our purpose was to investigate the biochemical composition of the coelomic fluid in first-trimester anembryonic pregnancies.Study Design: Coelomic and maternal serum were obtained from 17 anembryonic pregnancies and 17 apparently normal pregnancies between 7 and 12 weeks of gestation that were matched for gestational age. Electrolytes, total proteins, urea, creatinine, lactate, and human chorionic gonadotropin concentrations and pH were measured.Results: Significantly higher pH (p < 0.005) and bicarbonate levels (p < 0.001) and significantly lower total protein (p < 0.05), phosphate (p < 0.005), and human chorionic gonadotropin (p < 0.001) levels were found in coelomic fluid from anembryonic pregnancies compared with normal pregnancies. No difference was found for chloride, sodium, potassium, urea, creatinine, and lactate between the study and control groups.Conclusions: The fluid collected in anembryonic pregnancies is of exocoelomic origin and its biochemical characteristics reflect a failure of most placental biological mechanisms such as metabolic function, transport function, and endocrine activity.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
