Abstract
1. 1. The concentration of isocitrate and 2-oxoglutarate in cows' milk was determined in cows fed low- or high-fat diets. 2. 2. The concentration of 2-oxoglutarate in milk correlated positively with the short and medium chain fatty acids in milk fat. 3. 3. The concentration of isocitrate in milk correlated negatively with the short and medium chain fatty acids in milk fat. 4. 4. It is proposed that changes in the concentrations of these minor constituents of milk occur as a result of changes in their intracellular concentrations. In the present experiment these changes are probably the result of changes in the rate of fatty acid synthesis de novo in the mammary gland.
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