Abstract
The aim of this study was to investigate changes in the anterior segment of the eye after cycloplegia. A biometer combined with swept-source optical coherence tomography (SSOCT) was used for measurements. Patients with strabismus or amblyopia who underwent cycloplegia were included. The axial length, central corneal thickness, anterior chamber depth, and lens thickness were measured with the biometer–SSOCT system before and after cycloplegia. Altogether, 10 eyes of 10 patients (mean age 7.20 ± 3.08 years, range 4–14 years) were evaluated. The mean measurements before cycloplegia were 22.75 ± 0.96 mm axial length, 516 ± 33 μm central corneal thickness, 3.40 ± 0.21 mm anterior chamber depth, and 3.77 ± 0.26 mm lens thickness. The corresponding values after cycloplegia were 22.75 ± 0.95 mm, 519 ± 34 μm, 3.68 ± 0.16 mm, and 3.42 ± 0.20 mm, respectively. The mean lens thickness had significantly decreased (P < 0.001) after cycloplegia, and the mean anterior chamber depth had significantly increased (P < 0.001). The means of the axial length (P = 0.66) and central corneal thickness (P = 0.17) had not changed significantly. The change in lens thickness was significantly correlated with the change in anterior chamber depth (r = −0.73, P = 0.02). The new biometer–SSOCT combination proved useful for accurately detecting changes in the anterior segment of the eye after cycloplegia in pediatric patients. The biometer’s measurements indicated increased anterior chamber depth and decreased lens thickness after cycloplegia. The anterior chamber depth increased relative to the decrease in lens thickness.
Highlights
Refractive errors are related to amblyopia and strabismus in some pediatric patients
The axial length, central corneal thickness, anterior chamber depth, and lens thickness data were obtained with Argos (Suntec, Inc., Aichi, Japan), the biometer used in this study with SS-optical coherence tomography (OCT)
The lens thickness values had decreased in all patients, and the mean lens thickness had significantly decreased after cycloplegia (P < 0.001) (Fig 1)
Summary
Refractive errors are related to amblyopia and strabismus in some pediatric patients. Cycloplegic agents are used routinely during the examination in pediatric patients to investigate the correct refraction without accommodation [1,2,3,4,5,6]. Because the ciliary muscle controls accommodation by changing the thickness of the lens, the cycloplegic agent causes paralysis of the ciliary muscle, thereby causing loss of accommodation. Cyclopentolate and atropine are the agents most commonly used to achieve cycloplegia [1, 4, 7].
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