Abstract
The change in concentration of plasma zinc after the oral administration of zinc was used as an index of zinc absorption. The source of zinc was a multivitamin mineral supplement, which contained 25 mg of elemental zinc as zinc oxide. Taking the supplement without breakfast caused a significant increase (P<.01) in plasma zinc over the baseline concentration. Eating breakfast prior to taking the supplement prevented a rise in plasma zinc for at least three hours after taking the supplement. This suggests that a meal either inhibits the absorption of zinc from the supplement or reduces the rate of absorption, or increases turnover and/or excretion.
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