Abstract
THE nutrition of the chondrocytes of articular cartilage is derived in part at least from the synovial fluid, by diffusion through the matrix1. Many workers have studied the permeability of cartilage by observing the diffusion of dyes and other substances into the tissue, but few have noted the effect of ageing2–5. To this end, the penetration into cartilage of ‘Protargol’, a silver proteinate, has been compared in rabbits of two age-groups: (1) 3–4 months, (2) 21 months and older.
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