Abstract

Cerium oxide (CeO2) nanoparticles are regarded as one of the most promising materials for biomedical applications. Due to their antioxidant activity CeO2 nanoparticles are capable of protecting cells from oxidative stress induced by various physical or chemical factors. In this paper we have investigated the protective effect of CeO2 nanoparticles in the model of oxidative stress induced by low-temperature argon plasma, which is characterized by multiply damaging factors, including different types of radiation (ultraviolet and infrared), free radicals and reactive oxygen species. It was shown that citrate-stabilized cerium oxide nanoparticles protect primary embryonic mouse fibroblasts from the action of plasma, maintaining a high level of cell viability.

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