Abstract
Aim: To evaluate the clinical data and quantitative cerebrospinal fluidfor associations with the outcome of cryptococcal meningitis (CM) patients in the hospital. Patients & methods: We retrospectively analyzed a total of 139 CM patients comprising 108 without HIV and 31 with HIV admitted in a Jiang Xi hospital. Resμlts: We found that CM patients with the high fungal burden (≥10yeasts/μl) (26.3%) had a worse prognosis than those with the low fungal burden (<10yeasts/μl). (4.9%) (p=0.0007<0.05). Conclusion: In CM patients, a fungal burden of 10yeasts/μl in the first cerebrospinal fluid test may be used as an indicator of patient prognosis, and we can personalize patients' treatment based on the fungal burden to improve prognosis.
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