Abstract
Brain infarctions induce direct abnormalities within the damaged hemisphere and in distant areas, as well as indirect changes in the brain reflecting the lesion-induced deficit. As the patients recover, recovery-related changes occur. The lesion-related, deficit-related and recovery-related changes were studied by measurements of the regional cerebral metabolism and blood flow in patients with their first hemiparetic brain infarction. Since brain lesions are expected to affect cerebral networks subserving information processing and control of behaviour, multivariate types of image analysis were applied to functional brain imaging data. Here, we report our results on disease-related abnormalities and postlesional reorganisation of neural networks after sensorimotor stroke.
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