Abstract
Abstract Cerebral blood flow (CBF) and cerebral metabolic rate of oxygen (CMRo2) have been determined by the nitrous oxide method in five cases of severe barbiturate poisoning (blood barbiturate level 2.2−15.2 mg/100 ml). All cases needed prolonged artificial ventilation (IPPV) to survive. Mean CBF was 30±9 ml/100 g/min and mean CMRo2 was 1.5±0.4 ml/100 g/min. Within the temperature range studied, 31.7°C−37.8°C, body temperature (BT) was correlated to CMRo2 according to the equation BT = 6.6 × CMRo2 + 25, the correlation coefficient being 0.96 (p<0.01). A similar correlation was found between CBF and BT (r=0.93, p<0.05). The cerebral arteriovenous oxygen difference was normal and rather constant in spite of generally low values for arterial Pco2. There was no indication of inadequate oxygen supply to the brain.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
